| Date | Owner | Team | Dropped | Added |
|---|---|---|---|---|
| 4/8 | Ben | The Return of Big Ben | Basallo, Samuel | Langeliers, Shea |
| 4/9 | Connie | Connie's Clubbers | Wong, Connor | Ruiz, Keibert |
| 4/10 | Austin | Austin's Big Sticks | Cowser, Colton | Abreu, Wilyer |
| 4/12 | Kelly | Team LMD | Norby, Connor | Bregman, Alex |
| 4/15 | Matt | The Naturals | Steele, Justin | Fried, Max |
| 4/16 | Cathy | Cathy's Clowns | Bednar, David | Yates, Kirby |
| 4/16 | Richard Jr. | Big Bat Season | Snell, Blake | Fried, Max |
| 4/21 | Billy III | Goozer's Cadets | Robles, Victor | Abreu, Wilyer |
| 4/23 | Lily (NY) | Lily's Legends | Merrill, Jackson | Wood, James |
| 4/26 | Drew | Chicken Alfredo | Williams, Devin | Munoz, Andres |
| 4/27 | Kelley | Sally's Sluggers & Chuck-ers | Cowser, Colton | Crow-Armstrong, Pete |
| 5/4 | Tom Sr. | Ebbets Fielders | Gilbert, Logan | Yamamoto, Yoshinobu |
| 5/5 | Marchie | Buckstop | Snell, Blake | Gore, Mackenzie |
| 5/17 | Jack S. | The Jack Hammers | Westburg, Jordan | Turang, Brice |
| 5/26 | Matt | The Naturals | Crews, Dylan | Crow-Armstrong, Pete |
| 6/1 | Henry | The Eagles | Casas, Triston | Torkelson, Spencer |
| 6/3 | Jack S. | The Jack Hammers | Bregman, Alex | Caminero, Junior |
| 6/5 | Connie | Connie's Clubbers | Glasnow, Tyler | Rodon, Carlos |
| 6/9 | Sandra | Patchwork Diamonds | Santander, Anthony | Crow-Armstrong, Pete |
| 6/10 | Sandra | Patchwork Diamonds | Nola, Aaron | Webb, Logan |
| 6/10 | Tom Sr. | Ebbets Fielders | Langeliers, Shea | Smith, Will D |
| 6/11 | Marchie | Buckstop | Burnes, Corbin | Crochet, Garrett |
| 6/11 | Gayle | Frosty's Flakes | Burnes, Corbin | Crochet, Garrett |
| 6/15 | Mick | The Wyverns | Crews, Dylan | Anthony, Roman |
| 7/7 | Gary S. | Eastbound and Down | Sale, Chris | Crochet, Garrett |
| 7/9 | Hannah | Swing the Bat | King, Michael | Skubal, Tarik |
| 7/27 | Ray | Return to GloRAY | Crews, Dylan | Anthony, Roman |
| 7/27 | Mick | The Wyverns | Schwellenbach, Spencer | Brown, Hunter |
| 7/28 | Ray | Return to GloRAY | Doyle, Brenton | Crow-Armstrong, Pete |
| 7/31 | Drew | Chicken Alfredo | Santander, Anthony | Crow-Armstrong, Pete |
| 7/31 | Steve (NH) | Green Monsters | Campbell, Kristian | Torres, Gleyber |
| 8/3 | Tom Jr. | Duanesburg Coyotes | Alvarez, Yordan | Schwarber, Kyle |
| 8/3 | Tom Jr. | Duanesburg Coyotes | Santander, Anthony | Crow-Armstrong, Pete |
| 8/4 | Tyler | Banana Bombers | Lee, Korey | Goodman, Hunter |
| 8/16 | Henry | The Eagles | Houck, Tanner | Pivetta, Nick |
| 8/16 | Alyssa | — | Crawford, Kutter | Bello, Brayan |
| 8/20 | Ben | The Return of Big Ben | Williams, Carson | Perdomo, Geraldo |
| 8/24 | Nicole | Nic's Picks | Riley, Austin | Machado, Manny |
| 8/26 | Steve (NH) | Green Monsters | Wheeler, Zack | Gray, Sonny |
| 8/30 | Gary S. | Eastbound and Down | Toglia, Michael | Busch, Michael |
| 9/3 | Gayle | Frosty's Flakes | Hader, Josh | Diaz, Edwin |